Annual Report 2022

I.Achievement of Research Activities in 2022


M.Ogawa, R.Fukuda, R.Iwama, Y.Koyama, H.Horiuchi
srdA mutations suppress the rseA/cpsA deletion mutant conidiation defect in Aspergillus nidulans
 Scientific Reports 13: 4285 (2023)

A.Sato, Y.Ohnishi
The chromosomal evolutionary lineage of the genus Zygosaccharomyces
 FEMS Yeast Research, foad017,

K.Tamano, S.Nakai, H.Takayama,Y.Imai
Overexpression of a predicted transketolase gene and disruption of an α-1,3-glucan synthase gene in Aspergillus oryzae DGLA3 strain enhances the yield of free dihomo- γ-linolenic acid
 Bioscience, Biotechnology, and Biochemistry 87(4): 448 (2023)

II.Grant project

NISR provides research grants to researchers in the field of applied biology for the purpose of developing the fermentation and brewing industry, and building a sustainable society.

1) 2022 NISR Research Grant

Kenji KAI(Osaka Metropolitan University)
Generation and discovery of the bacterial polyynes with a pentayne substructure

Tomohisa KUZUYAMA(The University of Tokyo)
Mining of novel terpene cyclases from fungi and biological production of terpenoids

Chiho MINAKUCHI(The University of Tokyo)
How do the bacterial members interact with each other in a pyrene-degrading consortium?

Keisuke OBARA(Nagoya University)
Elucidation of lipid asymmetry signaling for prevention of fungal infections

Tomohiro SHIMADA(Meiji University)
Control of novel energy production by anaerobic respiration with using citrate via citrate response two-component system

Kan TANAKA(Tokyo Institute of Technology)
Regulatory mechanism of expression of chaperone protein genes (hsp genes) in cyanobacteria

Yota TSUGE(Kanazawa University)
Metabolic bottleneck in bacteria at non-proliferating elevated temperature

Hiroya YURIMOTO(Kyoto University)
Regulatory mechanism of gene expression depending on the methanol concentration in the yeast used for heterologous protein production

2) 2022 NISR Young Investigator Research Grant

Chihiro KADOOKA(Sojo University)         
Elucidation of capsular polysaccharide biosynthesis mechanism in Cryptococcus neoformans

Akira NISHIMURA(Nara Institute of Science and Technology)            
Clarification of inhibitory mechanism of proline utilization in fermentations and its application

Yoshihiro TOYA(Osaka University)           
Application of light inducible metabolic switch for enhancing bio-production in microorganism

3) 2022 NISR Sustainable fields Research Grant

Kengo INOUE(University of Miyazaki)
Improvement of microbial fuel cell using livestock waste by persistent bacteria in indigenous flora

Masahiro ITO(Toyo University)
Improvement of the function of membrane vesicles that uptake cesium ion and establishment of its recovery technology

Masafumi KAMEYA(The University of Tokyo)
CO2-based biopolymer synthesis and elucidation of a novel biopolymer degradation pathway

4) 2021 NISR Research Grant

Shigeki EHIRA(Tokyo Metropolitan University)
Complete conversion of sugars synthesized by photosynthesis into commodity products

Eiji MASAI(Nagaoka University of Technology)
Stereoselective catabolism of β-1 type lignin-derived aromatic isomers in Sphingobium sp. strain SYK-6

Hiromichi MINAMI(Ishikawa Prefectural University)
Fermentation production of plant alkaloids by synthetic biology for drug development

Toshiyuki WAKIMOTO(Hokkaido University)
Synthetic biology of non-ribosomal cyclopeptide

Seiya WATANABE(Ehime University)
Understanding of catalytic mechanism of flavin-containing dehydrogenases and its bioindustrial application

Toshiharu YAKUSHI(Yamaguchi University)
Role of the cell-surface oxidation system on the cell growth in acetic acid bacteria

5) 2021 NISR Young Investigator Research Grant

Ryo IWAMA(The University of Tokyo)                                                               
Contribution of membrane lipid unsaturation to temperature-dependent changes of secreted protein in the filamentous fungus Aspergillus oryzae

Daisuke KURITA(Hirosaki University)
Screening of drug candidates that inhibit ArfA-dependent ribosome rescue system

Yoshiya SETO(Meiji University)
Exploration of strigolactone-like molecules in phytopathogenic fungi

Mizuki TANAKA(Tokyo University of Agriculture and Technology)
Novel conidiation regulatory mechanism by N-end rule pathway in Aspergillus oryzae

Keiko UECHI(University of the Ryukyus)
Elucidation of molecular weight control system for fungal cell wall polysaccharide Nigeran and establishment of its fermentation production system

6) 2020 NISR Young Investigator Research Grant

Keisuke WADA(National Institute of Advanced Industrial Science and Technology (AIST))
Construction of an aerobic isobutanol-producing strain of Escherichia coli based on enzymatic and metabolic engineering

7) 2018 NISR Research Grant

Hiromi MAEKAWA(Kyushu University)
Application of the methylotrophic yeast sexual mechanism in an artificial mating type switching system

Back to Annual Reports